Cancer Therapy

Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides

Biomedical Engineering / Fluorescence Microscopy / Humans / Controlled release / Cancer Therapy / Female / Temperature / Peptides / Phase transition / Subcellular Localization / Cell nucleus / Time Factors / Neoplasms / Cell Proliferation / Drug Carriers / Cytoplasm / Antineoplastic Agents / Female / Temperature / Peptides / Phase transition / Subcellular Localization / Cell nucleus / Time Factors / Neoplasms / Cell Proliferation / Drug Carriers / Cytoplasm / Antineoplastic Agents

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Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice

Nephrology / Oncology / Urology / Immunology / Cancer / Treatment / Immunohistochemistry / Femtosecond Laser / Cornea / Immunology of the Gut / Near Infrared / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cancer treatment / Photodynamic Therapy / Cell Division / Signal Transduction / High Frequency / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Spectrum / Epidermal Growth Factor / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / High Spatial Resolution / Blood Vessel / Lymphatic System / Nude mice / Neutralizing antibodies / Vascular Endothelial Growth Factor / Tyrosine Kinase / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines / Treatment / Immunohistochemistry / Femtosecond Laser / Cornea / Immunology of the Gut / Near Infrared / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cancer treatment / Photodynamic Therapy / Cell Division / Signal Transduction / High Frequency / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Spectrum / Epidermal Growth Factor / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / High Spatial Resolution / Blood Vessel / Lymphatic System / Nude mice / Neutralizing antibodies / Vascular Endothelial Growth Factor / Tyrosine Kinase / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines

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Arsenic trioxide and neuroblastoma cytotoxicity

Clinical Trial / Bioenergetics / Cell Differentiation / Humans / Cancer Therapy / Multidrug Resistance / Drug Resistance / Cell Death / Arsenic trioxide / Neuroblastoma / Oxides / Antineoplastic Agents / Arsenicals / Brain Neoplasms / Biochemistry and cell biology / Multidrug Resistance / Drug Resistance / Cell Death / Arsenic trioxide / Neuroblastoma / Oxides / Antineoplastic Agents / Arsenicals / Brain Neoplasms / Biochemistry and cell biology

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Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells

Genetics / Epigenetics / Colorectal cancer / Humans / Glucose / Cancer Therapy / Ischemia / DNA methylation / Enzyme / Carbonic anhydrase / Carcinoma / Oxygen / Western blot / Tumor Progression / Biochemistry and cell biology / Colorectal Neoplasms / Cancer Therapy / Ischemia / DNA methylation / Enzyme / Carbonic anhydrase / Carcinoma / Oxygen / Western blot / Tumor Progression / Biochemistry and cell biology / Colorectal Neoplasms

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Análisis de satisfacción en varones que presentaban cáncer de próstata localizado tratados con prostatectomía radical o radioterapia: Aspectos Psicológicos y Sociales

Sexual Dysfunction / Quality of life / Prostate Cancer / Erectile dysfunction / Urinary incontinence / Cancer Therapy / Functional Assessment / STEM (short form) / Clinical Sciences / Radical Prostatectomy / Health Survey / Control Group / Cancer Therapy / Functional Assessment / STEM (short form) / Clinical Sciences / Radical Prostatectomy / Health Survey / Control Group

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Antitumor effect of gefitinib (‘Iressa’) on esophageal squamous cell carcinoma cell lines in vitro and in vivo

Flow Cytometry / Cell Cycle / Signal Transduction / Cell line / Humans / Cancer Therapy / Mice / Female / Animals / Kinase inhibitor / Oral Squamous Cell Carcinoma (OSCC) / Epidermal Growth Factor Receptor / Tyrosine Kinase Inhibitor / factor VIII / Growth Inhibition / Cell Proliferation / Cell Cycle Arrest / Antitumor Activity / Growth Factor / Antineoplastic Agents / Cell Sorting / Nude mice / Growth factor receptor / Quinazolines / Cancer Therapy / Mice / Female / Animals / Kinase inhibitor / Oral Squamous Cell Carcinoma (OSCC) / Epidermal Growth Factor Receptor / Tyrosine Kinase Inhibitor / factor VIII / Growth Inhibition / Cell Proliferation / Cell Cycle Arrest / Antitumor Activity / Growth Factor / Antineoplastic Agents / Cell Sorting / Nude mice / Growth factor receptor / Quinazolines

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In vitro biological activities of transmembrane superantigen staphylococcal enterotoxin A fusion protein

Genetics / Immunology / Flow Cytometry / Gene Therapy / Ovarian Cancer / Gene expression / Spleen / Cell line / Humans / Cancer Therapy / Escherichia coli / Mice / Enterotoxins / Female / Animals / Staphylococcus aureus / natural killer (NK) cell / Biological activity / Fusion Protein / Survival Time / NK Cell / Gene expression / Spleen / Cell line / Humans / Cancer Therapy / Escherichia coli / Mice / Enterotoxins / Female / Animals / Staphylococcus aureus / natural killer (NK) cell / Biological activity / Fusion Protein / Survival Time / NK Cell

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PET of Vascular Endothelial Growth Factor Receptor Expression

Nuclear medicine / Positron Emission Tomography / Gene expression / Nuclear / Humans / Cancer Therapy / Mice / Glioblastoma / Animals / Tumor Angiogenesis / Clinical Sciences / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Cancer Therapy / Mice / Glioblastoma / Animals / Tumor Angiogenesis / Clinical Sciences / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor

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Trastuzumab-Doxorubicin Conjugate Provides Enhanced Anti-Cancer Potency and Reduced Cardiotoxicity

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All-trans-retinoic acid induces manganese superoxide dismutase in human neuroblastoma through NF-κB

Gene expression / Nuclear Receptor / Free Radical / Cell line / Humans / Cancer Therapy / NF-kappa B / Superoxide Dismutase / Transcription Factor / Enzyme / Neuroblastoma / Time Dependent / DNA binding / Tretinoin / Acute Promyelocytic Leukemia / Biochemistry and cell biology / Enzyme Induction / Cancer Therapy / NF-kappa B / Superoxide Dismutase / Transcription Factor / Enzyme / Neuroblastoma / Time Dependent / DNA binding / Tretinoin / Acute Promyelocytic Leukemia / Biochemistry and cell biology / Enzyme Induction

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Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Humans / Cancer Therapy / Mice / Animals / Isoenzymes / Medicinal / Neoplasms / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Mice / Animals / Isoenzymes / Medicinal / Neoplasms / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor

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Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer\'s disease and target for cancer therapy

Mitochondria / Neuronal cell death / Mitochondrial DNA / Humans / Cancer Therapy / Peptides / Cell nucleus / Amino Acid Sequence / Base Sequence / Antineoplastic Agents / Peptides / Cell nucleus / Amino Acid Sequence / Base Sequence / Antineoplastic Agents

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Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor

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Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor

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An in vitro comparative study with furyl-1,4-quinones endowed with anticancer activities

Comparative Study / Protein synthesis / Software / Liver / Cancer Therapy / Mice / Animals / Male / Hepatocellular Carcinoma / Cell Death / Glutathione / Quinones / Cell Transplantation / Caspase / Rats / Wistar Rats / Biological activity / Physico chemical Properties / Cell Survival / Antineoplastic Agents / Protein Biosynthesis / Anticancer Drug / Adenosine Triphosphate / Safety Factor / Liver Tumor / Mice / Animals / Male / Hepatocellular Carcinoma / Cell Death / Glutathione / Quinones / Cell Transplantation / Caspase / Rats / Wistar Rats / Biological activity / Physico chemical Properties / Cell Survival / Antineoplastic Agents / Protein Biosynthesis / Anticancer Drug / Adenosine Triphosphate / Safety Factor / Liver Tumor

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Symptom control trials: a 20-year experience

Pain / Clinical Trial / Radiotherapy / Fatigue / Cancer treatment / Osteoporosis / Humans / Cancer Therapy / Anemia / Mucositis / Skin Diseases / Neoplasms / Cancer Patient / Cachexia / Anorexia / National Cancer Institute / Lymphedema / Antineoplastic Agents / Nervous System Diseases / Hot Flashes / Clinical Trials as Topic / Osteoporosis / Humans / Cancer Therapy / Anemia / Mucositis / Skin Diseases / Neoplasms / Cancer Patient / Cachexia / Anorexia / National Cancer Institute / Lymphedema / Antineoplastic Agents / Nervous System Diseases / Hot Flashes / Clinical Trials as Topic

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